Jacob Bethell ruled out of England's Australia white-ball tour
Coles and Jack have been called up to the ODI squad, while Bethell will fly home on Saturday to see a specialist about his right knee.
Jacob Bethell has been ruled out of England's white-ball tour of Australia on Wednesday, the England and Wales Cricket Board (ECB) said after a scan on his right knee.
The batter suffered a setback while training in Perth earlier this week, during his return from injury, the ECB said.
Because the winter ahead is busy, the board decided Bethell will travel back to the UK on Saturday to consult a specialist, it said.
James Coles and Eddie Jack have been named in the one-day international squad as replacements for Bethell and Josh Tongue, the ECB said.
Coles and Jack are scheduled to land in Perth on Thursday, the board added.
Separately, the England Women's squad will play three intra-squad red-ball matches and one fixture against Australia A before the Ashes, the ECB said.
In South Africa, the England Men's Blind team took a 1-0 lead, with captain David Howells taking charge of the final over, the board said.
The Blind side will now face their South African counterparts in a seven-match IT20 series.
The England men's team will play South Africa in a three-match Test series starting on Dec. 17, according to the release.
The ECB also said it supports the Equal Sport Project, a coalition of sporting organisations working toward a more equal future for women and girls in sport.
The ECB is the governing body for cricket in England and Wales, and it selects and manages the country's national men's and women's teams.
Squad changes like this are common on long tours, when players return home to deal with injuries before the next set of fixtures.